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LL-37

LL-37 is a naturally occurring antimicrobial peptide derived from the human cathelicidin protein. It is well-known for its ability to modulate immune responses, promote wound healing, and combat bacterial, viral, and fungal pathogens. LL-37 is provided in lyophilized powder form for research purposes exploring its role in immunity, inflammation, and tissue regeneration.

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Product Usage: For Research Use Only – Not for Human or Veterinary Use
This product is intended strictly for in vitro research and laboratory experimentation by qualified professionals. It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. The bodily introduction of this product into humans or animals is strictly prohibited by law. Any misuse, misbranding, or mislabeling of this product is a violation of federal regulations.

Description

Product Name:
LL-37
Chemical Information:
  • Molecular Formula: C205H340N60O53
  • Molecular Weight: 4492.11 g/mol
  • Sequence: H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
Molecular Structure:
Molecular Structure
Description:
LL-37 is a naturally occurring antimicrobial peptide derived from the human cathelicidin protein. It is well-known for its ability to modulate immune responses, promote wound healing, and combat bacterial, viral, and fungal pathogens. LL-37 is provided in lyophilized powder form for research purposes exploring its role in immunity, inflammation, and tissue regeneration.
Research Applications
LL-37 is actively researched for its potential to:
  • Combat Pathogens: Investigate its antimicrobial properties against bacterial, viral, and fungal infections.
  • Support Wound Healing: Study its ability to promote cellular repair and tissue regeneration in damaged areas.
  • Regulate Immune Responses: Examine its role in modulating inflammatory pathways to enhance immune balance.
  • Periodontal Disease: Explore its effectiveness in mitigating oral infections and promoting gum health in periodontal disease studies.
Storage and Handling
  • Store lyophilized powder at -20°C.
  • Once reconstituted, store at 2-8°C and use promptly.
  • Maintain aseptic techniques during handling to ensure sterility.
Product Specifications
  • Purity: ≥99% (HPLC Certified)
  • Appearance: Lyophilized white powder
  • Solubility: Soluble in bacteriostatic water
Important Note
LL-37 is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. Misuse of this product is strictly prohibited and may violate federal, state, or local laws.
References

This product is referenced in various scientific studies, including:

  1. Mookherjee, N., et al. (2006). “LL-37: A Cathelicidin with Antimicrobial and Immunomodulatory Properties.” Clinical Microbiology Reviews.
  2. Mizoguchi, H., et al. (2011). “Effect of LL-37 on Oral Pathogens and Periodontal Disease.” Journal of Periodontology.

Certificate of Analysis

At Pure Health Peptides, transparency is key. Every batch is third-party tested in the USA, with Certificates of Analysis (COAs) readily available for verification, giving researchers confidence in their work.

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