Product Name:

GLP-2 (SU) (Survodutide, BI 456906)

Chemical Information:

• Molecular Formula: C₁₉₂H₂₈₉N₄₇O₆₁
• Molecular Weight: ~4232 g/mol
• Sequence: 29-amino-acid synthetic peptide (acylated with C18 fatty di-acid, includes non-coded amino acid in position 2)
• Structure Class: Synthetic dual-receptor agonist (GLP-1R/GCGR) with fatty acid albumin-binding moiety

Molecular Structure:

Description:

GLP-2 (SU), also known as Survodutide (BI 456906), is a long-acting investigational peptide engineered to act as a dual agonist at both glucagon-like peptide-1 receptors (GLP-1R) and glucagon receptors (GCGR). A C18 fatty acid acylation prolongs half-life by promoting reversible albumin binding. This agent is supplied as a lyophilized powder, intended exclusively for in vitro laboratory research use.

Research Applications:

GLP-2 (SU) is suitable for controlled research protocols exploring:

• Mechanisms of dual GLP-1R and GCGR receptor activation in metabolic signaling
• Peptide pharmacokinetics associated with fatty acid acylation and albumin binding
• Energy balance modeling via combined effects on food intake and expenditure
• Metabolic disease modeling, including adiposity and hepatic lipid regulation

Storage and Handling:

• Store lyophilized powder at −20°C
• Once reconstituted, store at 2-8°C and use promptly
• Use aseptic technique to avoid contamination; product is not certified sterile

Product Specifications:

• Purity: ≥99% (HPLC Certified)
• Appearance: White lyophilized powder
• Solubility: Soluble in bacteriostatic water

Compliance Notice:

GLP-2 (SU) is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. Not FDA evaluated or approved. The purchaser affirms exclusive in vitro research use by qualified professionals. Misuse may violate federal or local regulations.