Product Name:

ARA-290 (Cibinetide Peptide)

Chemical Information:

• Molecular Formula: C₅₁H₈₄N₁₆O₂₁
• Molecular Weight: ~1257.3 g/mol
• Sequence: Asp-Glu-Leu-Asp-Ser-Thr-Ser-Ser-Glu-Glu-Leu-Leu-Lys-Glu-Arg (15-amino-acid erythropoietin Helix-B surface peptide)

Molecular Structure:

Description:

ARA-290, also known as cibinetide, is a synthetic 15–amino-acid peptide derived from the Helix-B surface region of erythropoietin (EPO). Unlike EPO, ARA-290 does not activate the classical EPOR receptor pathway. In controlled laboratory research, it is examined for its selective interaction with the EPOR/CD131 heteromeric complex, also referred to as the innate repair receptor (IRR). Supplied as a lyophilized peptide powder, ARA-290 is intended exclusively for in-vitro laboratory research where high-purity peptide material is required.

Research Applications: (In-Vitro Use Only)

ARA-290 is studied in controlled laboratory settings for:

• Characterization of EPOR/CD131 (IRR) peptide–receptor interactions
• Analysis of selective signaling pathways related to cytokine modulation
• Investigations of structure–function relationships in EPO-derived peptides
• Binding, stability, and physicochemical profiling in peptide research
• Laboratory assays exploring pathway specificity and receptor selectivity

Storage and Handling:

• Store lyophilized powder at −20 °C
• After reconstitution, maintain at 2–8 °C
• Use promptly after reconstitution
• Handle using standard aseptic laboratory technique

Product Specifications:

• Purity: ≥99% (HPLC Certified)
• Appearance: Lyophilized white to off-white powder
• Solubility: Soluble in aqueous laboratory buffers; solubility varies with pH and medium

Compliance Notice:

FOR RESEARCH USE ONLY. Not for human or veterinary use. Not evaluated by the FDA. By purchasing this product, the buyer acknowledges it will be used solely for in-vitro laboratory research and in accordance with all applicable regulations.